ZNF428

Across TCGA patient cohorts, ZNF428 protein abundance is significantly associated with the RNA expression of many other genes, with 12,363 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF428-associated genes across cancer lineages are CSRNP2, SOBP, and ADGRB2. Each is linked with ZNF428 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF428-to-partner and partner-to-ZNF428 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF428 versus CSRNP2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF428→partner) and Y-score (partner→ZNF428) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CSRNP2 →	+0.371	+0.257	.005	.005	3	5
HNSC	SOBP →	+0.781	+0.431	<.001	<.001	3	5
BRCA	ADGRB2 →	+1.239	+0.309	.001	.002	3	5
BRCA	IFT81 →	+0.476	+0.306	.003	.001	3	5
LUAD	SPATS2 →	+0.362	+0.244	.001	.001	3	5
BRCA	ZNF45 →	+0.814	+0.376	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,363 associations by consensus.

ZNF428 vs CSRNP2 — BRCA

Explore this scatter interactively →