ZNF428

Across TCGA cell cohorts, ZNF428 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF428-associated genes across cancer lineages are SPAG11A and OR8B4. Each is linked with ZNF428 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF428-to-partner and partner-to-ZNF428 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPAG11A grouped by ZNF428-low versus ZNF428-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF428→partner) and Y-score (partner→ZNF428) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SPAG11A →	+0.073	+6.022	<.001	.001	3	1
SKIN	OR8B4 →	+0.021	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SPAG11A by ZNF428 expression — SKIN

Explore this box plot interactively →