Across TCGA patient cohorts, ZNF425 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,468 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF425-associated proteins across cancer lineages are RO60, ASCC3, and HSP90B1. Each is linked with ZNF425 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF425-to-partner and partner-to-ZNF425 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF425→partner) and Y-score (partner→ZNF425) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RO60 →	+0.248	+0.467	<.001	<.001	3	5
BRCA	ASCC3 →	-0.237	-0.564	.003	.001	3	5
BRCA	HSP90B1 →	-0.381	-0.573	<.001	<.001	3	5
BRCA	UBE2J1 →	-0.522	-0.468	<.001	.004	3	5
GBM	DNAJB11 →	-0.294	-0.402	<.001	<.001	3	5
GBM	TXNDC5 →	-0.626	-0.637	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,468 associations by consensus.

Exploration

ZNF425 survival (RNA) · tumor vs normal (RNA) · all ZNF425 data types