Across TCGA cell cohorts, ZNF425 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF425-associated genes across cancer lineages are ASB17, SYT10, and HOXB1. Each is linked with ZNF425 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF425-to-partner and partner-to-ZNF425 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF425→partner) and Y-score (partner→ZNF425) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	2
BLOOD_Lymphoma	SYT10 →	+0.017	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	HOXB1 →	+0.014	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.024	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	HTR5A →	+0.142	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	CLEC1B →	+0.584	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ZNF425 survival (RNA) · tumor vs normal (RNA) · all ZNF425 data types