ZNF419

Across TCGA patient cohorts, ZNF419 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,846 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF419-associated proteins across cancer lineages are TRIM28, ARHGAP35, and SAE1. Each is linked with ZNF419 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF419-to-partner and partner-to-ZNF419 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF419 versus TRIM28 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF419→partner) and Y-score (partner→ZNF419) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM28 →	+0.440	+0.587	<.001	<.001	3	7
BRCA	ARHGAP35 →	+0.322	+0.404	.002	.002	3	6
LSCC	SAE1 →	+0.305	+0.514	<.001	<.001	3	5
BRCA	ZSCAN18 →	+0.565	+0.657	<.001	<.001	3	5
BRCA	EPM2AIP1 →	+0.560	+0.556	<.001	<.001	3	5
CCRCC	PPIF →	-0.470	-0.332	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,846 associations by consensus.

ZNF419 vs TRIM28 — LSCC

Explore this scatter interactively →