ZNF419

Across TCGA cell cohorts, ZNF419 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF419-associated GO terms across cancer lineages are Vesicle budding from membrane, COPII-coated vesicle budding, and Negative regulation of myoblast fusion. Each is linked with ZNF419 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF419-to-partner and partner-to-ZNF419 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by ZNF419-low versus ZNF419-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF419→partner) and Y-score (partner→ZNF419) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Vesicle budding from membrane →	+0.075	+0.776	<.001	<.001	3	17
PANCREAS	COPII-coated vesicle budding →	+0.081	+0.850	<.001	.001	3	15
OVARY	Negative regulation of myoblast fusion →	+0.112	+1.017	<.001	<.001	3	15
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.110	+1.017	<.001	<.001	3	14
BLOOD_Myeloma	Vesicle coating →	+0.082	+0.996	<.001	<.001	3	14
BREAST	Golgi vesicle transport →	+0.060	+1.066	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,363 associations by consensus.

Vesicle budding from membrane by ZNF419 expression — CNS

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