Across TCGA patient cohorts, ZNF418 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,926 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF418-associated proteins across cancer lineages are PHLDB1, AGO1, and FERMT2. Each is linked with ZNF418 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF418-to-partner and partner-to-ZNF418 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF418→partner) and Y-score (partner→ZNF418) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PHLDB1 →	+0.303	+0.392	<.001	.004	3	7
GBM	AGO1 →	+0.304	+0.749	<.001	<.001	3	7
COAD	FERMT2 →	+0.567	+0.314	<.001	<.001	3	7
LSCC	UTRN →	+0.342	+1.151	<.001	<.001	3	6
LSCC	ILK →	+0.376	+0.720	<.001	.001	3	6
BRCA	ZSCAN18 →	+0.491	+0.590	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,926 associations by consensus.

Exploration

ZNF418 survival (RNA) · tumor vs normal (RNA) · all ZNF418 data types