Across TCGA cell cohorts, ZNF418 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,036 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF418-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of transcription initiation by RNA polymerase II, and DNA-templated transcription initiation. Each is linked with ZNF418 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF418-to-partner and partner-to-ZNF418 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF418→partner) and Y-score (partner→ZNF418) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of myoblast fusion →	+0.083	+1.351	<.001	.001	3	11
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.048	+1.415	.002	.002	3	11
BLOOD_Lymphoma	DNA-templated transcription initiation →	+0.058	+0.738	<.001	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.075	+0.630	<.001	.007	3	10
LIVER	Transcription initiation at RNA polymerase II promoter →	+0.081	+1.410	<.001	.004	3	10
URINARY_TRACT	Regulation of transcription elongation by RNA polymerase II →	+0.053	+1.598	.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,036 associations by consensus.

Exploration

ZNF418 survival (RNA) · tumor vs normal (RNA) · all ZNF418 data types