ZNF416

Across TCGA patient cohorts, ZNF416 protein abundance is significantly associated with the RNA expression of many other genes, with 11,497 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF416-associated genes across cancer lineages are PACSIN2, ELF4, and GSR. Each is linked with ZNF416 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF416-to-partner and partner-to-ZNF416 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF416 versus PACSIN2 in CCRCC, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF416→partner) and Y-score (partner→ZNF416) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PACSIN2 →	+0.461	+1.005	.002	<.001	3	1
CCRCC	ELF4 →	-0.618	-1.004	<.001	<.001	3	1
CCRCC	GSR →	+0.811	+1.005	.001	<.001	3	1
CCRCC	CBLL1 →	-0.328	-1.005	<.001	<.001	3	1
CCRCC	HOXA3 →	-0.549	-1.306	.004	.003	3	1
CCRCC	CASP2 →	-0.433	-1.015	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,497 associations by consensus.

ZNF416 vs PACSIN2 — CCRCC

Explore this scatter interactively →