ZNF416

Across TCGA patient cohorts, ZNF416 mutation is significantly associated with the RNA expression of many other genes, with 3,299 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF416-associated genes across cancer lineages are MIR6074, MTND6P20, and LINC01909. Each is linked with ZNF416 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF416-to-partner and partner-to-ZNF416 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6074 grouped by ZNF416-low versus ZNF416-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF416→partner) and Y-score (partner→ZNF416) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6074 →	+0.267	+5.219	<.001	.002	3	2
BLCA	MTND6P20 →	+0.059	+7.640	<.001	.009	3	2
UCEC	LINC01909 →	+0.355	+2.641	<.001	<.001	3	2
UCEC	ERFL →	+0.274	+1.643	.009	.003	3	2
COAD	IGHEP2 →	+0.369	+3.692	<.001	.004	3	2
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,299 associations by consensus.

MIR6074 by ZNF416 expression — SKCM

Explore this box plot interactively →