ZNF416

Across TCGA cell cohorts, ZNF416 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible ZNF416-associated genes across cancer lineages are KRT32, C4orf17, and SCN2B. Each is linked with ZNF416 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF416-to-partner and partner-to-ZNF416 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT32 grouped by ZNF416-low versus ZNF416-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF416→partner) and Y-score (partner→ZNF416) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRT32 →	+0.005	+3.285	<.001	.009	3	1
BLOOD_Myeloma	C4orf17 →	+0.022	+4.000	.006	.002	3	1
BLOOD_Myeloma	SCN2B →	+0.010	+3.754	<.001	.002	3	1
BLOOD_Myeloma	C1orf105 →	+0.080	+4.000	.002	.002	3	1
BLOOD_Myeloma	FAM183A →	+0.311	+3.514	.004	.008	3	1
BLOOD_Myeloma	CD200R1L →	+0.022	+3.514	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

KRT32 by ZNF416 expression — BLOOD_Myeloma

Explore this box plot interactively →