ZNF410

Across TCGA patient cohorts, ZNF410 mutation is significantly associated with the RNA expression of many other genes, with 2,741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF410-associated genes across cancer lineages are MIR4727, RNU6-171P, and IPPKP1. Each is linked with ZNF410 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF410-to-partner and partner-to-ZNF410 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4727 grouped by ZNF410-low versus ZNF410-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF410→partner) and Y-score (partner→ZNF410) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4727 →	+0.250	+2.381	.001	.009	3	3
SKCM	RNU6-171P →	+0.297	+4.897	<.001	.002	3	2
SKCM	IPPKP1 →	+0.052	+4.639	<.001	<.001	3	2
PRAD	CYCSP42 →	+0.089	+7.939	<.001	.008	3	2
UCEC	MIR6803 →	+0.098	+4.156	<.001	.004	3	2
SKCM	HAUS1P3 →	+0.030	+4.147	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,741 associations by consensus.

MIR4727 by ZNF410 expression — UCEC

Explore this box plot interactively →