Across TCGA patient cohorts, ZNF407 mutation is significantly associated with the RNA expression of many other genes, with 7,866 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF407-associated genes across cancer lineages are MTA2, PIP4K2C, and ZFR. Each is linked with ZNF407 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF407-to-partner and partner-to-ZNF407 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF407→partner) and Y-score (partner→ZNF407) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTA2 →	+0.383	+2.364	<.001	<.001	3	5
UCEC	PIP4K2C →	+0.409	+2.022	<.001	<.001	3	5
LUSC	ZFR →	+0.355	+2.521	.009	.009	3	5
COAD	TXNL1 →	+0.459	+2.960	<.001	<.001	3	5
LUAD	NASP →	+0.550	+2.735	.002	.003	3	5
UCEC	ELOCP19 →	+0.372	+1.404	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,866 associations by consensus.

Exploration

ZNF407 survival (RNA) · tumor vs normal (RNA) · all ZNF407 data types