Across TCGA cell cohorts, ZNF407 mutation is significantly associated with the RNA expression of many other genes, with 509 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF407-associated genes across cancer lineages are FBXO40, KRTAP5-10, and KIAA1191. Each is linked with ZNF407 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF407-to-partner and partner-to-ZNF407 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF407→partner) and Y-score (partner→ZNF407) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FBXO40 →	+0.013	+4.017	.002	.007	3	2
SKIN	KRTAP5-10 →	+0.030	+3.505	<.001	<.001	3	2
BLOOD_Leukemia	KIAA1191 →	+0.443	+2.489	.002	.007	3	2
BLOOD_Leukemia	MGME1 →	+0.416	+2.489	.001	.007	3	2
BLOOD_Leukemia	UXT →	+0.379	+2.608	.004	.005	3	2
BLOOD_Leukemia	MOCS2 →	+0.638	+2.489	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 509 associations by consensus.

Exploration

ZNF407 survival (RNA) · tumor vs normal (RNA) · all ZNF407 data types