Across TCGA pan-cancer cohorts, ZNF397 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF397 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF397 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZNF397 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD and CCRCC are the cancer types where ZNF397 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.848	0.581	.015	10	view →
CCRCC	OS	Median	All	1.000	0.589	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZNF397 tumor-vs-normal RNA expression · all ZNF397 data types