Across TCGA patient cohorts, ZNF397 protein abundance is significantly associated with the RNA expression of many other genes, with 2,918 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF397-associated genes across cancer lineages are CTSB, GEMIN7, and DRP2. Each is linked with ZNF397 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF397-to-partner and partner-to-ZNF397 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF397→partner) and Y-score (partner→ZNF397) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CTSB →	-0.582	-0.201	.007	.005	3	4
BRCA	GEMIN7 →	+0.297	+0.303	.004	.006	3	3
HNSC	DRP2 →	-0.429	-0.399	<.001	.002	3	2
HNSC	PADI2 →	-1.417	-0.450	<.001	.002	3	2
HNSC	MMP14 →	-0.863	-0.446	<.001	.002	3	2
HNSC	PHLDB3 →	+0.701	+0.547	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

Exploration

ZNF397 survival (RNA) · tumor vs normal (RNA) · all ZNF397 data types