Across TCGA cell cohorts, ZNF397 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,648 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF397-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Positive regulation of DNA repair, and Regulation of cytoplasmic mRNA processing body assembly. Each is linked with ZNF397 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF397-to-partner and partner-to-ZNF397 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF397→partner) and Y-score (partner→ZNF397) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.076	+0.759	<.001	<.001	3	17
BONE	Positive regulation of DNA repair →	+0.067	+1.086	<.001	<.001	3	15
BONE	Regulation of cytoplasmic mRNA processing body assembly →	+0.120	+1.368	<.001	<.001	3	14
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.131	+1.169	<.001	<.001	3	14
BONE	Regulation of hemostasis →	-0.219	-1.367	.002	<.001	3	14
BONE	RNA catabolic process →	+0.058	+0.964	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,648 associations by consensus.

Exploration

ZNF397 survival (RNA) · tumor vs normal (RNA) · all ZNF397 data types