Across TCGA patient cohorts, ZNF396 mutation is significantly associated with the RNA expression of many other genes, with 2,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF396-associated genes across cancer lineages are LINC02706, DUXAP5, and ACTG1P13. Each is linked with ZNF396 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF396-to-partner and partner-to-ZNF396 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF396→partner) and Y-score (partner→ZNF396) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02706 →	+0.095	+6.048	<.001	<.001	3	3
SKCM	DUXAP5 →	+0.109	+4.594	<.001	<.001	3	2
HNSC	ACTG1P13 →	+0.058	+5.435	<.001	.005	3	2
BRCA	OFD1P11Y →	+0.023	+7.471	<.001	.008	3	2
UCEC	MIR4445 →	+0.123	+3.893	<.001	.006	3	2
SKCM	TTTY11 →	+0.089	+4.469	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,859 associations by consensus.

Exploration

ZNF396 survival (RNA) · tumor vs normal (RNA) · all ZNF396 data types