Across TCGA cell cohorts, ZNF395 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF395-associated genes across cancer lineages are CRNN, CHRNB3, and CD81. Each is linked with ZNF395 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF395-to-partner and partner-to-ZNF395 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF395→partner) and Y-score (partner→ZNF395) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CRNN →	+0.259	+4.867	<.001	.009	3	1
SKIN	CHRNB3 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	CD81 →	+0.711	+3.131	.005	.008	3	1
LARGE_INTESTINE	ALDH6A1 →	+1.026	+3.064	.001	.009	3	1
LARGE_INTESTINE	PNKD →	+0.541	+3.125	.002	.008	3	1
LARGE_INTESTINE	MFSD14A →	+0.645	+3.064	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ZNF395 survival (RNA) · tumor vs normal (RNA) · all ZNF395 data types