ZNF394

Across TCGA patient cohorts, ZNF394 mutation is significantly associated with the RNA expression of many other genes, with 673 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF394-associated genes across cancer lineages are SNORD126, RN7SL616P, and MIR4727. Each is linked with ZNF394 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF394-to-partner and partner-to-ZNF394 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD126 grouped by ZNF394-low versus ZNF394-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF394→partner) and Y-score (partner→ZNF394) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SNORD126 →	+0.383	+3.962	<.001	.003	3	3
CESC	RN7SL616P →	+0.113	+5.144	<.001	.003	3	2
HNSC	MIR4727 →	+0.696	+5.303	<.001	.006	3	2
BLCA	MIR4771-2 →	+0.435	+2.851	.003	.004	3	2
LIHC	RNA5SP437 →	+0.277	+3.962	<.001	.003	3	2
LIHC	MIR648 →	+0.260	+3.894	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 673 associations by consensus.

SNORD126 by ZNF394 expression — LIHC

Explore this box plot interactively →