ZNF394

Across TCGA cell cohorts, ZNF394 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,240 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF394-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Peptidyl-serine modification, and Negative regulation of translational initiation. Each is linked with ZNF394 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF394-to-partner and partner-to-ZNF394 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by ZNF394-low versus ZNF394-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF394→partner) and Y-score (partner→ZNF394) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.201	+0.373	.001	.001	3	16
LUNG_NSCLC_LUAD	Peptidyl-serine modification →	+0.058	+0.617	<.001	<.001	3	12
BONE	Negative regulation of translational initiation →	+0.154	+0.464	<.001	.001	3	12
LUNG_NSCLC_LUAD	Peptidyl-serine phosphorylation →	+0.057	+0.630	<.001	<.001	3	10
BONE	Regulation of translational initiation →	+0.098	+0.565	<.001	<.001	3	10
SKIN	Endosomal transport →	+0.064	+0.808	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,240 associations by consensus.

Pre-mRNA catabolic process by ZNF394 expression — BONE

Explore this box plot interactively →