ZNF385D

Across TCGA patient cohorts, ZNF385D mutation is significantly associated with the RNA expression of many other genes, with 3,134 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF385D-associated genes across cancer lineages are H2AZ1, WASHC3P1, and RNU6ATAC30P. Each is linked with ZNF385D in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF385D-to-partner and partner-to-ZNF385D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2AZ1 grouped by ZNF385D-low versus ZNF385D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385D→partner) and Y-score (partner→ZNF385D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H2AZ1 →	+0.501	+2.091	.002	<.001	3	4
CESC	WASHC3P1 →	+0.061	+4.516	<.001	.004	3	3
CESC	RNU6ATAC30P →	+0.360	+4.591	<.001	<.001	3	3
UCEC	IDH1-AS1 →	+0.683	+1.936	<.001	.002	3	3
UCEC	NDUFC1 →	+0.437	+2.080	<.001	<.001	3	3
SKCM	RRP9 →	+0.279	+1.821	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,134 associations by consensus.

H2AZ1 by ZNF385D expression — UCEC

Explore this box plot interactively →