ZNF385D

Across TCGA patient cohorts, ZNF385D mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF385D-associated genes across cancer lineages are STAT3_pY705, C-Raf, and 14-3-3_beta. Each is linked with ZNF385D in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF385D-to-partner and partner-to-ZNF385D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by ZNF385D-low versus ZNF385D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385D→partner) and Y-score (partner→ZNF385D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.393	-2.321	<.001	.005	3	3
COAD	C-Raf →	+0.183	+3.169	.005	.018	3	3
SKCM	14-3-3_beta →	-0.113	-2.169	.008	.002	3	2
UCEC	eEF2 →	+0.324	+1.700	.007	.042	3	2
SKCM	EGFR →	-0.116	-2.000	.033	.029	3	2
UCEC	JNK_pT183_Y185 →	-0.163	-1.584	.004	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

STAT3_pY705 by ZNF385D expression — UCEC

Explore this box plot interactively →