ZNF385D

Across TCGA cell cohorts, ZNF385D mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF385D-associated genes across cancer lineages are IL4, BHLHE23, and NPFFR1. Each is linked with ZNF385D in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF385D-to-partner and partner-to-ZNF385D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL4 grouped by ZNF385D-low versus ZNF385D-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385D→partner) and Y-score (partner→ZNF385D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL4 →	+1.532	+3.007	<.001	.007	3	1
BLOOD_Leukemia	BHLHE23 →	+1.113	+3.409	.001	.008	3	1
BLOOD_Leukemia	NPFFR1 →	+0.011	+3.359	<.001	.002	3	1
BLOOD_Leukemia	CHST9 →	+0.018	+3.387	.001	.005	3	1
BLOOD_Leukemia	WNT3A →	+0.043	+3.169	<.001	.008	3	1
BLOOD_Leukemia	TRAT1 →	+2.479	+3.754	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

IL4 by ZNF385D expression — BLOOD_Leukemia

Explore this box plot interactively →