Across TCGA cell cohorts, ZNF385C mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF385C-associated genes across cancer lineages are TAS2R7, CDX4, and PTH2R. Each is linked with ZNF385C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF385C-to-partner and partner-to-ZNF385C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385C→partner) and Y-score (partner→ZNF385C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAS2R7 →	+0.011	+4.022	<.001	.006	3	1
LARGE_INTESTINE	CDX4 →	+0.009	+3.632	<.001	.003	3	1
LARGE_INTESTINE	PTH2R →	+1.132	+3.453	<.001	.009	3	1
LARGE_INTESTINE	PROKR1 →	+0.044	+3.725	.003	.008	3	1
LARGE_INTESTINE	LIPJ →	+0.072	+3.684	<.001	.009	3	1
LARGE_INTESTINE	KRTAP12-3 →	+0.043	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

ZNF385C survival (RNA) · tumor vs normal (RNA) · all ZNF385C data types