ZNF385B

Across TCGA patient cohorts, ZNF385B mutation is significantly associated with the RNA expression of many other genes, with 3,099 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF385B-associated genes across cancer lineages are OFD1P6Y, MRPL17, and MAD2L1. Each is linked with ZNF385B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF385B-to-partner and partner-to-ZNF385B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P6Y grouped by ZNF385B-low versus ZNF385B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385B→partner) and Y-score (partner→ZNF385B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OFD1P6Y →	+0.009	+4.537	<.001	.006	3	3
UCEC	MRPL17 →	+0.274	+2.024	.006	.005	3	3
UCEC	MAD2L1 →	+0.676	+2.415	.001	.003	3	3
UCEC	STOML2 →	+0.387	+2.040	.003	.001	3	3
SKCM	ZMYND19 →	+0.526	+2.826	<.001	<.001	3	3
UCEC	CIAO2B →	+0.302	+1.737	.008	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,099 associations by consensus.

OFD1P6Y by ZNF385B expression — COAD

Explore this box plot interactively →