ZNF385B

Across TCGA cell cohorts, ZNF385B mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF385B-associated genes across cancer lineages are USP17L3, CER1, and SPAG11B. Each is linked with ZNF385B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF385B-to-partner and partner-to-ZNF385B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L3 grouped by ZNF385B-low versus ZNF385B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385B→partner) and Y-score (partner→ZNF385B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	USP17L3 →	+0.022	+4.922	<.001	.009	3	1
STOMACH	CER1 →	+0.022	+4.432	.005	.003	3	1
STOMACH	SPAG11B →	+0.057	+4.285	<.001	.007	3	1
STOMACH	TEX26 →	+0.037	+4.285	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	TOPAZ1 →	+0.125	+4.357	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	DUXA →	+0.030	+4.209	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

USP17L3 by ZNF385B expression — BLOOD_Leukemia

Explore this box plot interactively →