ZNF385A

Across TCGA patient cohorts, ZNF385A mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF385A-associated genes across cancer lineages are ASNS, ATM, and Caspase-7-cleavedD198. Each is linked with ZNF385A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF385A-to-partner and partner-to-ZNF385A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF385A-low versus ZNF385A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385A→partner) and Y-score (partner→ZNF385A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.412	+3.321	.003	.009	3	2
UCEC	ATM →	-0.517	-2.446	.003	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.652	+2.000	.005	.010	3	2
UCEC	eEF2 →	+0.429	+2.000	.002	.010	3	1
UCEC	A-Raf_pS299 →	-0.154	-2.000	.001	.010	3	1
UCEC	ERK2 →	+0.280	+2.906	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ASNS by ZNF385A expression — UCEC

Explore this box plot interactively →