ZNF385A

Across TCGA cell cohorts, ZNF385A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF385A-associated genes across cancer lineages are FEZF2, TAFA1, and CDR1. Each is linked with ZNF385A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF385A-to-partner and partner-to-ZNF385A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FEZF2 grouped by ZNF385A-low versus ZNF385A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF385A→partner) and Y-score (partner→ZNF385A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FEZF2 →	+0.020	+4.273	<.001	.006	3	1
BLOOD_Leukemia	TAFA1 →	+0.886	+4.149	<.001	.003	3	1
BLOOD_Leukemia	CDR1 →	+0.057	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FEZF2 by ZNF385A expression — LARGE_INTESTINE

Explore this box plot interactively →