ZNF37A

Across TCGA patient cohorts, ZNF37A mutation is significantly associated with the RNA expression of many other genes, with 4,985 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF37A-associated genes across cancer lineages are SSX2B, MRPL49, and FCGR1A. Each is linked with ZNF37A in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF37A-to-partner and partner-to-ZNF37A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSX2B grouped by ZNF37A-low versus ZNF37A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF37A→partner) and Y-score (partner→ZNF37A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SSX2B →	+0.019	+5.763	<.001	.001	3	3
UCEC	MRPL49 →	+0.611	+3.321	<.001	<.001	3	2
UCEC	FCGR1A →	+0.671	+2.169	<.001	<.001	3	2
UCEC	SAP18 →	+0.300	+4.021	<.001	<.001	3	2
UCEC	OXSM →	+0.372	+1.903	<.001	<.001	3	2
UCEC	ATP5F1A →	+0.341	+1.654	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,985 associations by consensus.

SSX2B by ZNF37A expression — HNSC

Explore this box plot interactively →