ZNF37A

Across TCGA patient cohorts, ZNF37A mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF37A-associated genes across cancer lineages are ASNS, eIF4E, and JNK2. Each is linked with ZNF37A in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF37A-to-partner and partner-to-ZNF37A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF37A-low versus ZNF37A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF37A→partner) and Y-score (partner→ZNF37A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.401	+1.678	<.001	.021	3	3
UCEC	eIF4E →	+0.204	+2.584	.003	<.001	3	2
UCEC	JNK2 →	+0.201	+1.874	.002	.002	3	2
UCEC	MSH2 →	-0.234	-2.196	.002	.009	3	2
UCEC	PDCD4 →	-0.546	-3.807	<.001	<.001	3	2
UCEC	Shc_pY317 →	-0.139	-1.584	.006	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

ASNS by ZNF37A expression — UCEC

Explore this box plot interactively →