ZNF366

Across TCGA patient cohorts, ZNF366 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,026 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF366-associated proteins across cancer lineages are TNS2, VWF, and PLAC9. Each is linked with ZNF366 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF366-to-partner and partner-to-ZNF366 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF366 versus TNS2 in CCRCC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF366→partner) and Y-score (partner→ZNF366) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TNS2 →	+0.465	+0.899	<.001	<.001	3	8
OV	VWF →	+0.525	+0.343	<.001	<.001	3	8
UCEC	PLAC9 →	+1.359	+0.478	<.001	<.001	3	8
UCEC	PLCL1_S569 →	+0.911	+0.401	<.001	.005	3	8
UCEC	PPP1R12B →	+1.114	+0.420	<.001	.003	3	8
UCEC	PPP1R12C →	+0.391	+0.421	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,026 associations by consensus.

ZNF366 vs TNS2 — CCRCC

Explore this scatter interactively →