ZNF366

Across TCGA cell cohorts, ZNF366 RNA expression is significantly associated with the go_rna of many other GO terms, with 653 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF366-associated GO terms across cancer lineages are Negative regulation of biomineral tissue development, Cellular response to calcium ion starvation, and Epithelial cilium movement involved in extracellular fluid movement. Each is linked with ZNF366 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF366-to-partner and partner-to-ZNF366 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of biomineral tissue development grouped by ZNF366-low versus ZNF366-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF366→partner) and Y-score (partner→ZNF366) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of biomineral tissue development →	+0.104	+0.376	<.001	.007	3	4
SOFT_TISSUE	Cellular response to calcium ion starvation →	+0.115	+0.110	<.001	<.001	3	4
SOFT_TISSUE	Epithelial cilium movement involved in extracellular fluid movement →	-0.406	-0.066	.004	.007	3	4
BONE	Regulation of natural killer cell differentiation →	+0.308	+0.005	<.001	.007	3	4
SOFT_TISSUE	Positive regulation of erythrocyte differentiation →	+0.076	+0.112	<.001	.004	3	3
SOFT_TISSUE	Positive regulation of mRNA processing →	+0.127	+0.108	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 653 associations by consensus.

Negative regulation of biomineral tissue development by ZNF366 expression — BLOOD_Leukemia

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