ZNF365

Across TCGA patient cohorts, ZNF365 mutation is significantly associated with the RNA expression of many other genes, with 2,534 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF365-associated genes across cancer lineages are MFSD12, POC1A, and NDUFAF2. Each is linked with ZNF365 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF365-to-partner and partner-to-ZNF365 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MFSD12 grouped by ZNF365-low versus ZNF365-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF365→partner) and Y-score (partner→ZNF365) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MFSD12 →	+0.337	+1.862	.003	<.001	3	3
UCEC	POC1A →	+0.416	+2.153	.005	<.001	3	3
UCEC	NDUFAF2 →	+0.375	+1.858	.003	.004	3	3
UCEC	ATP5MG →	+0.311	+2.279	<.001	<.001	3	3
COAD	CXXC4 →	-0.723	-3.432	.003	.005	3	3
COAD	ELP5 →	+0.438	+3.513	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,534 associations by consensus.

MFSD12 by ZNF365 expression — UCEC

Explore this box plot interactively →