ZNF365

Across TCGA cell cohorts, ZNF365 mutation is significantly associated with the RNA expression of many other genes, with 1,141 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF365-associated genes across cancer lineages are SNU13, CIB3, and CCDC134. Each is linked with ZNF365 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF365-to-partner and partner-to-ZNF365 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNU13 grouped by ZNF365-low versus ZNF365-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF365→partner) and Y-score (partner→ZNF365) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SNU13 →	+0.428	+3.358	.008	.003	3	2
LUNG_NSCLC_LUAD	CIB3 →	+0.355	+3.754	<.001	<.001	3	2
LARGE_INTESTINE	CCDC134 →	+0.829	+3.459	<.001	<.001	3	2
LARGE_INTESTINE	POLDIP3 →	+0.486	+3.362	.005	.002	3	2
LARGE_INTESTINE	TAB1 →	+0.525	+3.237	.003	.003	3	2
LARGE_INTESTINE	TNRC6B →	+0.886	+2.850	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

SNU13 by ZNF365 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →