ZNF362

Across TCGA cell cohorts, ZNF362 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,527 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF362-associated GO terms across cancer lineages are Negative regulation of transcription initiation by RNA polymerase II, Negative regulation of DNA-templated transcription initiation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF362 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF362-to-partner and partner-to-ZNF362 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription initiation by RNA polymerase II grouped by ZNF362-low versus ZNF362-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF362→partner) and Y-score (partner→ZNF362) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.169	+1.576	.001	.002	3	15
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.169	+1.576	.001	.002	3	15
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+1.124	<.001	<.001	3	15
STOMACH	Negative regulation of myoblast fusion →	+0.112	+1.096	<.001	<.001	3	15
STOMACH	Positive regulation of double-strand break repair →	+0.071	+1.050	.007	.007	3	14
STOMACH	Negative regulation of gene expression, epigenetic →	+0.068	+1.312	.004	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,527 associations by consensus.

Negative regulation of transcription initiation by RNA polymerase II by ZNF362 expression — STOMACH

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