Across TCGA pan-cancer cohorts, ZNF355P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZNF355P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF355P RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF355P is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and LUAD are the cancer types where ZNF355P tumor–normal differential expression is most reproducible.