ZNF354B

Across TCGA patient cohorts, ZNF354B protein abundance is significantly associated with the RNA expression of many other genes, with 289 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF354B-associated genes across cancer lineages are SEPTIN3, MTMR4, and CFAP92. Each is linked with ZNF354B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF354B-to-partner and partner-to-ZNF354B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF354B versus SEPTIN3 in HNSC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF354B→partner) and Y-score (partner→ZNF354B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN3 →	+0.857	+2.867	<.001	.002	3	1
HNSC	MTMR4 →	+0.972	+2.762	.005	.002	3	1
HNSC	CFAP92 →	+1.085	+2.308	.006	.002	3	1
HNSC	ABCC5 →	+1.798	+2.308	.008	.002	3	1
HNSC	HSDL2 →	+0.732	+2.308	.002	.002	3	1
HNSC	KIAA1217 →	+0.757	+2.787	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 289 associations by consensus.

ZNF354B vs SEPTIN3 — HNSC

Explore this scatter interactively →