ZNF354B

Across TCGA cell cohorts, ZNF354B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,024 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF354B-associated GO terms across cancer lineages are Termination of RNA polymerase II transcription, Microtubule organizing center organization, and Regulation of RNA splicing. Each is linked with ZNF354B in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF354B-to-partner and partner-to-ZNF354B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase II transcription grouped by ZNF354B-low versus ZNF354B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF354B→partner) and Y-score (partner→ZNF354B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Termination of RNA polymerase II transcription →	+0.128	+1.163	<.001	<.001	3	15
BONE	Microtubule organizing center organization →	+0.078	+0.688	.001	.001	3	15
BONE	Regulation of RNA splicing →	+0.088	+0.741	<.001	<.001	3	14
URINARY_TRACT	Nucleotide-excision repair →	+0.067	+1.044	.001	.009	3	14
BONE	Mismatch repair →	+0.090	+0.593	.007	.005	3	14
URINARY_TRACT	mRNA splice site recognition →	+0.147	+1.146	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,024 associations by consensus.

Termination of RNA polymerase II transcription by ZNF354B expression — OESOPHAGUS

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