ZNF354A

Across TCGA patient cohorts, ZNF354A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF354A-associated proteins across cancer lineages are NPM1, DDX41, and SSRP1. Each is linked with ZNF354A in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF354A-to-partner and partner-to-ZNF354A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF354A versus NPM1 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF354A→partner) and Y-score (partner→ZNF354A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NPM1 →	+0.385	+0.481	.002	.001	3	6
LSCC	DDX41 →	+0.252	+0.521	<.001	<.001	3	5
GBM	SSRP1 →	+0.452	+0.407	<.001	<.001	3	5
OV	HNRNPAB →	+0.378	+0.433	<.001	<.001	3	5
GBM	RBM22 →	+0.303	+0.464	<.001	.002	3	5
GBM	PHAX →	+0.294	+0.471	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,849 associations by consensus.

ZNF354A vs NPM1 — OV

Explore this scatter interactively →