ZNF350

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF350 mutation is significantly associated with the RNA expression of many other genes, with 3,168 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF350-associated genes across cancer lineages are RN7SL754P, CHST13, and BCAM. Each is linked with ZNF350 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF350-to-partner and partner-to-ZNF350 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL754P grouped by ZNF350-low versus ZNF350-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF350→partner) and Y-score (partner→ZNF350) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCRN7SL754P →+0.175+5.447<.001.00533
UCECCHST13 →-0.470-3.438.009.00532
UCECBCAM →-1.009-2.700.001.00532
UCECZNF724 →+0.525+1.914.002.00932
UCECMFSD14C →+0.667+3.032<.001<.00132
UCECPRIM1 →+0.700+3.743<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,168 associations by consensus.

RN7SL754P by ZNF350 expression — LIHC

Box plot of RN7SL754P in ZNF350-low vs ZNF350-high samples in LIHC.

Explore this box plot interactively →

Exploration