ZNF346

Across TCGA cell cohorts, ZNF346 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF346-associated genes across cancer lineages are BAAT, OR10Q1, and TAFA1. Each is linked with ZNF346 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF346-to-partner and partner-to-ZNF346 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAAT grouped by ZNF346-low versus ZNF346-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF346→partner) and Y-score (partner→ZNF346) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BAAT →	+0.492	+3.273	<.001	.006	3	1
LARGE_INTESTINE	OR10Q1 →	+0.075	+2.657	.007	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	NAT8B →	+0.661	+3.889	.003	<.001	3	1
LARGE_INTESTINE	LRRC3C →	+0.257	+4.144	<.001	<.001	3	1
LARGE_INTESTINE	CELA3B →	+0.162	+2.855	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

BAAT by ZNF346 expression — LARGE_INTESTINE

Explore this box plot interactively →