ZNF341

Across TCGA pan-cancer cohorts, ZNF341 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ZNF341 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ZNF341 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF341 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRP, UCEC, and BRCA are the cancer types where ZNF341 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	II,III,IV	0.148	0.771	<.001	27	view →
UCEC	DFS	Median	All	0.961	0.618	.009	22	view →
BRCA	OS	Median	All	0.628	0.924	.003	20	view →
LUAD	OS	Median	III,IV	0.223	0.677	.006	15	view →
SKCM	OS	Median	III,IV	0.524	0.851	.012	6	view →
STAD	DFS	Median	III,IV	0.149	0.606	.004	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ZNF341–KIRP (OS)

Open the KIRP breakdown →