ZNF341

Across TCGA patient cohorts, ZNF341 mutation is significantly associated with the RNA expression of many other genes, with 4,690 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF341-associated genes across cancer lineages are NDUFA12, CIB1, and RPS19BP1. Each is linked with ZNF341 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF341-to-partner and partner-to-ZNF341 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFA12 grouped by ZNF341-low versus ZNF341-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF341→partner) and Y-score (partner→ZNF341) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFA12 →	+0.307	+2.633	<.001	<.001	3	3
UCEC	CIB1 →	+0.445	+2.447	.002	.001	3	3
UCEC	RPS19BP1 →	+0.319	+3.931	.004	<.001	3	3
UCEC	ATAD3A →	+0.438	+3.839	<.001	<.001	3	3
SKCM	CINP →	+0.413	+3.870	<.001	<.001	3	3
SKCM	AKR1A1 →	+0.320	+1.658	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,690 associations by consensus.

NDUFA12 by ZNF341 expression — UCEC

Explore this box plot interactively →