ZNF341

Across TCGA patient cohorts, ZNF341 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF341-associated genes across cancer lineages are Cyclin-B1, PRDX1, and ERK2. Each is linked with ZNF341 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF341-to-partner and partner-to-ZNF341 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ZNF341-low versus ZNF341-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF341→partner) and Y-score (partner→ZNF341) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.532	+2.115	.009	.017	3	3
SKCM	PRDX1 →	+0.243	+2.000	.034	.029	3	3
UCEC	ERK2 →	+0.166	+1.807	.019	.025	3	2
SKCM	PCNA →	+0.266	+2.321	<.001	.032	3	2
UCEC	Caspase-7-cleavedD198 →	+0.848	+1.926	<.001	.008	3	2
UCEC	Di-Ras3 →	-0.113	-1.861	.038	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Cyclin-B1 by ZNF341 expression — UCEC

Explore this box plot interactively →