ZNF341

Across TCGA cell cohorts, ZNF341 mutation is significantly associated with the RNA expression of many other genes, with 202 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF341-associated genes across cancer lineages are PRLHR, WFDC12, and BHLHA9. Each is linked with ZNF341 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF341-to-partner and partner-to-ZNF341 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRLHR grouped by ZNF341-low versus ZNF341-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF341→partner) and Y-score (partner→ZNF341) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	PRLHR →	+0.030	+5.000	<.001	.005	3	1
KIDNEY	WFDC12 →	+0.066	+5.000	<.001	.005	3	1
KIDNEY	BHLHA9 →	+0.036	+5.000	<.001	.005	3	1
KIDNEY	TEX48 →	+0.133	+5.000	<.001	.005	3	1
PANCREAS	OR6V1 →	+0.019	+5.000	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.045	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 202 associations by consensus.

PRLHR by ZNF341 expression — KIDNEY

Explore this box plot interactively →