ZNF341-AS1

Across TCGA pan-cancer cohorts, ZNF341-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF341-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher ZNF341-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF341-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

PAAD, ESCA, and HNSC are the cancer types where ZNF341-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	All	0.343	0.561	<.001	37	view →
ESCA	DFS	Median	All	0.437	0.613	.002	26	view →
HNSC	DFS	Median	IV	0.714	0.569	.006	26	view →
UCS	DFS	Tertile	IV	0.975	0.237	.024	24	view →
UVM	DFS	Quartile	III,IV	0.047	0.670	<.001	22	view →
KIRP	DFS	Tertile	All	0.781	0.899	.007	20	view →
CESC	DFS	Median	All	0.775	0.864	.008	18	view →
COAD	DFS	Tertile	All	0.615	0.776	.012	16	view →
LUAD	OS	Tertile	All	0.788	0.860	.016	13	view →
STAD	OS	Median	All	0.391	0.646	.029	8	view →
KIRC	DFS	Median	IV	0.245	0.404	.029	7	view →
LIHC	OS	Quartile	All	0.669	0.857	.003	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF341-AS1–PAAD (DFS)

Open the PAAD breakdown →