Across TCGA cell cohorts, ZNF34 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF34-associated genes across cancer lineages are COX4I2, LHCGR, and GPR6. Each is linked with ZNF34 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF34-to-partner and partner-to-ZNF34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF34→partner) and Y-score (partner→ZNF34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	COX4I2 →	+0.098	+5.228	<.001	.005	3	1
LARGE_INTESTINE	LHCGR →	+0.029	+3.297	.002	.002	3	1
LARGE_INTESTINE	GPR6 →	+0.005	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	OR2Z1 →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

ZNF34 survival (RNA) · tumor vs normal (RNA) · all ZNF34 data types