Across TCGA pan-cancer cohorts, ZNF33CP RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ZNF33CP’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF33CP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF33CP is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.
KIRC, KIRP, and THCA are the cancer types where ZNF33CP tumor–normal differential expression is most reproducible.