Across TCGA patient cohorts, ZNF33A mutation is significantly associated with the RNA expression of many other genes, with 4,382 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF33A-associated genes across cancer lineages are PPP1R8, AURKA, and KIFC1. Each is linked with ZNF33A in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF33A-to-partner and partner-to-ZNF33A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF33A→partner) and Y-score (partner→ZNF33A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R8 →	+0.364	+1.769	<.001	.003	3	4
LUAD	AURKA →	+1.033	+3.333	<.001	.005	3	4
LUAD	KIFC1 →	+1.203	+2.830	<.001	.001	3	4
CESC	KRTAP19-8 →	+0.124	+3.507	<.001	.005	3	3
SKCM	ACACA →	+0.515	+2.913	.003	.001	3	3
LUAD	FAM83D →	+1.072	+2.593	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,382 associations by consensus.

Exploration

ZNF33A survival (RNA) · tumor vs normal (RNA) · all ZNF33A data types